You may experience dizziness, and if this persists or worsens, promptly inform your doctor or pharmacist.
This medication can induce daytime sleepiness. Notify your doctor if you experience daytime drowsiness, as your dosage may require adjustment.
Keep in mind that your doctor has prescribed this medication because they have assessed that its benefits outweigh the risk of side effects. Many individuals using this medication do not experience serious side effects.
Notify your doctor immediately if you encounter any serious side effects, such as memory loss, alterations in mental state or behavior (e.g., new or worsening depression, unusual thoughts, suicidal ideation, hallucinations, confusion, agitation, aggressive behavior, anxiety).
While severe allergic reactions to this medication are rare, seek medical assistance immediately if you observe symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.
Precautions
Before initiating zolpidem, inform your doctor or pharmacist about any known allergies to it or other substances. This product may contain inactive components that could trigger allergic reactions or other complications. Consult your pharmacist for further information.
Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of kidney or liver disease, mental health issues (e.g., depression, suicidal thoughts), personal or family history of substance use disorder, sleepwalking, respiratory conditions (e.g., COPD, sleep apnea), or a certain muscle disease (myasthenia gravis).
The effects of this medication may persist into the following day. If you slept less than 7 to 8 hours or took other medications inducing drowsiness, or if you are more susceptible to this drug, you may feel awake but lack clarity for driving. You might also experience dizziness or blurred/double vision. Alcohol or marijuana can exacerbate dizziness. Refrain from driving or operating machinery until at least 8 hours have elapsed since taking this medication. Additionally, avoid alcoholic beverages. If you use marijuana, discuss this with your doctor.
Children may be more susceptible to the side effects of zolpidem, particularly dizziness and hallucinations.
Older adults may be more prone to the side effects of this medication, including dizziness, confusion, unsteadiness, and excessive drowsiness, which can elevate the risk of falls.
Inform your doctor or dentist about all products you use, including prescription drugs, nonprescription drugs, and herbal products, before undergoing surgery.
During pregnancy, use this medication only if absolutely necessary. Infants born to mothers who used this drug late in the last trimester may exhibit unusual sleepiness, breathing difficulties, limpness, or withdrawal symptoms. Seek medical attention promptly if you notice any unusual symptoms in your newborn. Discuss the risks and benefits with your doctor.
A small quantity of this medication passes into breast milk and may have adverse effects on nursing infants, such as unusual sleepiness, breathing difficulties, or limpness. Seek medical attention immediately if you observe any unusual symptoms in your baby. Consult your doctor regarding the necessity to pump and discard breast milk during treatment and for 23 hours following a dose of this medication to mitigate the risk of adverse effects in your baby. Seek advice from your doctor before breastfeeding.
Interactions
Drug interactions can alter the efficacy of your medications or heighten the risk of serious side effects. This document does not encompass all potential drug interactions. Maintain a record of all products you utilize (including prescription/nonprescription drugs and herbal supplements) and disclose it to your doctor and pharmacist. Refrain from initiating, discontinuing, or adjusting the dosage of any medications without your doctor’s consent.
A product that may interact with this drug is sodium oxybate.
Other medications can influence the elimination of zolpidem from your system, potentially affecting its effectiveness. Examples include azole antifungals (e.g., ketoconazole), rifampin, St. John’s Wort, among others.
The likelihood of severe side effects (such as slow or shallow breathing, profound drowsiness, or dizziness) may escalate if this medication is combined with other products that induce drowsiness or respiratory problems. Inform your doctor or pharmacist if you are consuming other products such as opioid pain relievers or cough suppressants (e.g., codeine, hydrocodone), alcohol, marijuana (cannabis), other sleep or anxiety medications (e.g., alprazolam, lorazepam, zopiclone), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or antihistamines (e.g., cetirizine, diphenhydramine).
Examine the labels on all your medications (e.g., allergy or cough-and-cold products) as they may contain ingredients that induce drowsiness. Consult your pharmacist regarding the safe utilization of these products.
Conclusion
The prolonged use of Ambien, or zolpidem, for a decade raises significant considerations regarding its efficacy, safety, and potential long-term effects. While Ambien can effectively manage insomnia in the short term, extended usage may lead to tolerance, dependence, and withdrawal symptoms upon cessation. Moreover, the risk of adverse effects, such as cognitive impairment, drowsiness, and dependency, increases with prolonged use. It is imperative for individuals who have been taking Ambien for ten years or longer to regularly reassess their treatment plan with healthcare providers, explore alternative therapies, and consider lifestyle modifications to address underlying sleep issues. Open communication with healthcare professionals is essential to mitigate risks and ensure the ongoing management of insomnia in a safe and sustainable manner.
Authoritative References:
1. National Institute on Drug Abuse (NIDA). (2020). Prescription CNS Depressants DrugFacts.
Retrieved from: https://nida.nih.gov/publications/drugfacts/prescription-cns-depressants
2. Mayo Clinic. (2023). Zolpidem (Oral Route) – Proper Use and Precautions.
Available at: https://www.mayoclinic.org/drugs-supplements/zolpidem-oral-route/precautions/drg-20061195
3. American Academy of Sleep Medicine (AASM). (2022). Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults.
DOI: 10.5664/jcsm.8988